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September 23, 2025CureusOpen Access

Rescue In Vitro Maturation of a Germinal Vesicle Oocyte Leading to Pregnancy in a Case of Unexplained Infertility

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Authors

EAElham A AkbariZKZakwan KhraitNKNatalia Kondakova

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Overview

Case report shows pregnancy after rescue in vitro maturation and preimplantation genetic testing in an individual with infertility, indicating advanced techniques may aid outcomes.

Key Points

  • Successful singleton pregnancy achieved through rescue in vitro maturation of immature oocytes.
  • Four immature germinal vesicle-stage oocytes were cultured, with two developing into euploid blastocysts.
  • This assessment was conducted using preimplantation genetic testing to confirm viability of the embryos.
  • The findings emphasize the value of tailored assisted reproductive technology approaches, particularly for patients with poor ovarian reserve.

Cite This Study

Akbari et al. (2025) studied this question.

synapsesocial.com/papers/68d4757f31b076d99fa6cd19https://doi.org/10.7759/cureus.92989
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