Single-Cell Lipidomics: Performance Evaluation Across Four Liquid Chromatography Mass Spectrometry (LC-MS) Systems

Q: What type of study is this?

This is a Quantitative Study study (also classified as: Experimental Study).

Melanie J. Bailey; Johanna von Gerichten; Kyle D. G. Saunders; Matt Spick

doi:10.1039/d5an00851d

January 1, 2025The AnalystOpen Access

Single-Cell Lipidomics: Performance Evaluation Across Four Liquid Chromatography Mass Spectrometry (LC-MS) Systems

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Key Points

Single-cell lipidomics provides insights into heterogeneous cell populations, enhancing disease understanding.
Evaluation across different LC-MS systems shows varying performance levels in lipidomic analysis.
Methodologies involved include lipid extraction, analysis through liquid chromatography, and mass spectrometry.
Highlighting the need for standardized approaches to facilitate wider applicability in clinical settings.

Implication

Assessment of lipidomics technology in investigating cancer and cardiovascular disease implications.

Abstract

Single-cell lipidomics holds tremendous promise for understanding a wide range of pathological conditions involving heterogenous cell populations, including infection, cancer, diabetes, and cardiovascular disease and yet its widespread adoption has...

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Cite This Study

Bailey et al. (2025) studied this question.

synapsesocial.com/papers/68d4757f31b076d99fa6cd76 https://doi.org/10.1039/d5an00851d

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Single-Cell Lipidomics: Performance Evaluation Across Four Liquid Chromatography Mass Spectrometry (LC-MS) Systems

Key Points

Implication

Abstract

Discussion

Cite This Study

Single-Cell Lipidomics: Performance Evaluation Across Four Liquid Chromatography Mass Spectrometry (LC-MS) Systems

Key Points

Implication

Abstract

Discussion

Cite This Study

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