ExoTMS transcranial magnetic stimulation for the reduction of binge eating symptoms.

Transcranial magnetic stimulation (TMS) is an emerging treatment for binge eating (BE). TMS uses noninvasive magnetic pulses to stimulate the prefrontal cortex, which plays a role in decision-making and self-regulation. Early research suggests that TMS can reduce BE episodes by modulating brain activity linked to cravings and compulsive behavior. This article aims to evaluate the efficacy and safety of a novel TMS device with ExoTMS™ Technology for alleviating BE symptoms. Subjects underwent six TMS sessions and a 1-month follow-up. The Binge Eating Scale (BES) was administered at baseline, posttreatment, and follow-up to assess symptom severity. Weight was recorded at the same intervals. Therapy comfort was evaluated after the sixth session. The Subject Satisfaction Questionnaire was completed posttreatment and at follow-up. Adverse events and side effects were monitored throughout the study. Data from two identically designed studies were pooled for analysis. A total of 38 subjects were analyzed. BES scores significantly decreased posttreatment (-37.8%, p < 0.001) and at follow-up (-47.9%, p < 0.001). At 1 month, 73.7% of subjects achieved BE remission. Average weight loss was -1.3 ± 1.1 kg posttreatment and -1.8 ± 1.3 kg at follow-up. Comfort was rated positively by 92.1% of participants. At follow-up, 89.5% reported reduced cravings and snacking, 86.8% noted improved self-control and well-being, and 94.7% were satisfied with the treatment. TMS shows promise as a safe and effective intervention for reducing BE symptoms, supported by both objective clinical measures and subjective patient-reported outcomes.