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September 23, 2025

Regulatory Roles of MicroRNAs in Female and Male Human Reproduction: A Narrative Review.

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Authors

MKMohadeseh KhoshandamLNLeila NaserpourMGMohammad Taghi Hedayati Goudarzi

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Overview

This narrative review explores miRNAs' roles in male and female reproduction, highlighting key biomarkers related to infertility.

Key Points

  • Aberrant microrna expression patterns are associated with infertility in both genders.
  • A total of 72 high-quality studies were reviewed to understand microrna roles in reproductive function.
  • Specific micrornas can influence spermatogenesis and oogenesis, indicating their potential as biomarkers.
  • The review provides insights into microrna expression related to conditions like polycystic ovary syndrome and endometriosis.

Cite This Study

Khoshandam et al. (2025) studied this question.

synapsesocial.com/papers/68d4759031b076d99fa6d475https://doi.org/10.30476/ijms.2025.104375.3797
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1MiRNAs’ impact on human reproduction: their roles as diagnostic biomarkers2026
  2. 2MicroRNAs as Regulators of Reproductive Function: From Gametogenesis to Pregnancy2026
  3. 3MicroRNAs in spermatogenesis dysfunction and male infertility: clinical phenotypes, mechanisms and potential diagnostic biomarkers2024 · 48 citations
  4. 4MicroRNAs in Male Fertility2024 · 10 citations
  5. 5Unraveling the microRNAs, key players in folliculogenesis and ovarian diseases2024 · 12 citations