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This is a Experimental Study study.

In vivo Pharmacological Evaluation of the Anti-inflammatory and Analgesic Effects of Cola hispida Methanol Leaf Extract and Its Fractions

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Pharmacological assessment reveals potent anti-inflammatory and analgesic properties of cola hispida, suggesting its use in ethnomedicine.

Ethyl acetate fraction of cola hispida showed up to 80% inhibition of paw oedema, demonstrating strong anti-inflammatory effects.
Pain relief was observed with CHHF, significantly reducing paw licking by 36% in the formalin test’s late phase at 200 mg/kg.
Administration of the methanol leaf extract showed no toxicity up to 5000 mg/kg in mice, indicating safety for use.
Flavonoids and phenolic acids in the extract likely mediate the observed effects, supporting its traditional medicinal use.

Ani et al. (2025) studied this question.

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View Full Paper

Ask AI

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Authors

Pharmacological assessment reveals potent anti-inflammatory and analgesic properties of cola hispida, suggesting its use in ethnomedicine.

Ethyl acetate fraction of cola hispida showed up to 80% inhibition of paw oedema, demonstrating strong anti-inflammatory effects.
Pain relief was observed with CHHF, significantly reducing paw licking by 36% in the formalin test’s late phase at 200 mg/kg.
Administration of the methanol leaf extract showed no toxicity up to 5000 mg/kg in mice, indicating safety for use.
Flavonoids and phenolic acids in the extract likely mediate the observed effects, supporting its traditional medicinal use.

Ani et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark