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September 15, 2025Anatolian Current Medical JournalOpen Access

Receptor gene expressions and their association with biochemical parameters in primary hyperparathyroidism patients

Özge Karabıyık Acar

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Key Points

Lower calcium-sensing receptor expression was found in small adenomas, indicating a potential biomarker for PHPT.
Analysis revealed significant correlations between gene expression levels and biochemical parameters, such as serum calcium and PTH.
RNA from parathyroid adenomas was analyzed using reverse transcription quantitative PCR to assess gene expression.
The findings may help in understanding the molecular mechanisms underlying primary hyperparathyroidism.

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Implication

Gene expression profiles of PTH, CaSR, VDR, and FGFR1 in parathyroid adenomas correlate with biochemical parameters.

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Cite This Study

Özge Karabıyık Acar (2025) studied this question.

synapsesocial.com/papers/68d475a031b076d99fa6de56 https://doi.org/10.38053/acmj.1752081

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