Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 23, 2025Anatolian Current Medical JournalOpen Access

Receptor gene expressions and their association with biochemical parameters in primary hyperparathyroidism patients

View Full Paper
Ask AI
Bookmark
Share

Authors

ÖAÖzge Karabıyık Acar

Discussion

Loading...

Member takes

Overview

Gene expression profiles of PTH, CaSR, VDR, and FGFR1 in parathyroid adenomas correlate with biochemical parameters.

Key Points

  • Lower calcium-sensing receptor expression was found in small adenomas, indicating a potential biomarker for PHPT.
  • Analysis revealed significant correlations between gene expression levels and biochemical parameters, such as serum calcium and PTH.
  • RNA from parathyroid adenomas was analyzed using reverse transcription quantitative PCR to assess gene expression.
  • The findings may help in understanding the molecular mechanisms underlying primary hyperparathyroidism.

Cite This Study

Özge Karabıyık Acar (2025) studied this question.

synapsesocial.com/papers/68d475a031b076d99fa6de56https://doi.org/10.38053/acmj.1752081
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Immunohistochemical Expression of CaSR, VDR, and AMA in Parathyroid Tumors in Relation to Hypercalcemia Severity in Primary Hyperparathyroidism2026
  2. 2Immunohistochemical Expression of CaSR, VDR, and AMA in Parathyroid Tumors Linked to Hypercalcemia Severity in Primary Hyperparathyroidism2025
  3. 3mRNA expression of vitamin D receptor, calcium-sensing receptor, cyclin D1, and PTH in symptomatic and asymptomatic primary hyperparathyroidism2024 · 1 citations
  4. 4Longitudinal Analysis of Biochemical, Imaging, and Adenoma Size Changes in Primary Hyperparathyroidism2026
  5. 5Parathyroid histology in normocalcemic and hypercalcemic primary hyperparathyroidism with hypercalciuric renal stones2026