Evaluation of Immune System Components in Dogs With Protein‐Losing Enteropathy Compared to Healthy Controls

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Prospective study shows reduced immunoglobulin levels in dogs with protein‐losing enteropathy, indicating immune deficiency.

Dogs with protein‐losing enteropathy showed significantly lower serum immunoglobulin IgG levels than healthy controls, suggesting immune dysfunction.
Lower concentrations of IgM were also observed in dogs with protein‐losing enteropathy compared to healthy controls, indicating broader immune deficiencies.
Evaluation was performed by measuring serum IgA, IgG, and IgM concentrations through ELISA and gene expression via quantitative PCR.
These findings highlight the need for careful monitoring of immune system components in dogs with protein‐losing enteropathy.

Moore et al. (2025) studied this question.

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