Prospective observational study reveals clinical presentation and etiological factors in 66 patients with acute pancreatitis, highlighting the role of gallstones.
Objective: Acute pancreatitis (AP) is a common gastrointestinal emergency with varying severity and outcomes. Understanding its clinico-pathological profile and immediate hospital outcomes is crucial for early intervention and improving prognosis. The aim of this study to evaluate the clinical presentation, etiological factors, severity, and immediate outcomes of acute pancreatitis in hospitalized patients. Methods: A prospective observational study was conducted on 66 patients diagnosed with AP based on the Revised Atlanta Classification (2012). Demographic data, clinical features, laboratory parameters, imaging findings, and hospital outcomes were analyzed. Results: The mean age of patients was 45.2±12.5 years, with a male predominance (63.6%). The most common etiology was gallstones (51.5%), followed by alcohol (30.3%). Abdominal pain (100%) and vomiting (72.7%) were the most frequent symptoms. According to severity, 57.6% had mild, 30.3% moderate, and 12.1% severe AP. Complications included pancreatic necrosis (9.1%), pseudocyst formation (6.1%), and acute kidney injury (7.6%). The mortality rate was 4.5%. Conclusion: Gallstone disease remains the leading cause of AP. Early recognition of severe cases and prompt management can reduce complications and mortality.
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Singh et al. (2025) studied this question.
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