Overview of harziane diterpenoids: discovery, bioactivity, total synthesis and biosynthesis

Q: What type of study is this?

This is a Literature Review study (also classified as: Experimental Study).

Mingmin Wu; Jinmei Li; Wencong Yang

doi:10.1039/d5ob01393c

January 1, 2025Organic & Biomolecular Chemistry

Overview of harziane diterpenoids: discovery, bioactivity, total synthesis and biosynthesis

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Key Points

Harziane diterpenoids showcase notable structural complexity with their intricate 6/5/7/4 carbocyclic scaffold.
The first identified harziane diterpenoid, harziandione, emerged from Trichoderma harzianum, highlighting this source's significance.
Research outlines both total synthesis and biosynthesis methods critical for analyzing these complex compounds.
Understanding bioactivity of harziane diterpenoids may inform medicinal applications and natural product chemistry.

Implication

Overview reveals unique harziane diterpenoids' bioactivity and total synthesis in Trichoderma harzianum, indicating potential applications.

Abstract

Harziane diterpenoids constitute a unique class of diterpenoids distinguished by their intricate 6/5/7/4 carbocyclic scaffold, presenting notable structural complexity. Since the first harziane diterpenoid, harziandione, was described from Trichoderma harzianum ...

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Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/68d6d8768b2b6861e4c3e790 https://doi.org/10.1039/d5ob01393c

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Overview of harziane diterpenoids: discovery, bioactivity, total synthesis and biosynthesis

Key Points

Implication

Abstract

Discussion

Cite This Study

Overview of harziane diterpenoids: discovery, bioactivity, total synthesis and biosynthesis

Key Points

Implication

Abstract

Discussion

Cite This Study

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