What type of study is this?

This is a Quantitative Study study.

September 24, 2025PeerJOpen Access

Bacterial microbiome profiles of the inflamed terminal ileum mucosa in active Crohn’s disease patients

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Authors

JYJuan Juan YinSuzhou Municipal Hospital THTong HuSuzhou Municipal Hospital LZLiping ZhangBeijing University of Chinese Medicine

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Implication

This analysis identifies key microbial differences in inflamed versus noninflamed mucosa from Crohn's disease patients, suggesting dysbiosis may contribute to disease progression.

Key Points

Active Crohn's disease patients show distinct bacterial profiles in inflamed mucosa compared to noninflamed tissues.
A total of 753 operational taxonomic units (OTUs) were unique to inflamed mucosa in Crohn's patients.
Dysbiosis was observed with specific upregulation of genera like Methylobacterium and Bifidobacterium in inflamed regions.
Findings imply that the microbial shifts in mucosa may play a role in the pathogenesis of Crohn's disease.

Cite This Study

Yin et al. (2025) studied this question.

synapsesocial.com/papers/68d6d8978b2b6861e4c3eb3a https://doi.org/10.7717/peerj.19959

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Implication

This analysis identifies key microbial differences in inflamed versus noninflamed mucosa from Crohn's disease patients, suggesting dysbiosis may contribute to disease progression.

Bacterial microbiome profiles of the inflamed terminal ileum mucosa in active Crohn’s disease patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Bacterial microbiome profiles of the inflamed terminal ileum mucosa in active Crohn’s disease patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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