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September 24, 2025InfectionOpen Access

Hospital-acquired pneumonia caused by multidrug-resistant Streptococcus pneumoniae serotype 15A

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Case of a 71-year-old man with MDR pneumonia in ICU, highlighting treatment challenges associated with nosocomial infections.

MDR Streptococcus pneumoniae caused early-onset hospital-acquired pneumonia, complicating post-surgery recovery.
Ceftriaxone resistance was identified (MIC 16 µg/mL), necessitating a change to levofloxacin for effective treatment.
The case underscores the importance of susceptibility testing for effective management of HAP due to antibiotic-resistant strains.
Ongoing monitoring of invasive infections from vaccine-escape serotypes like 15A is crucial for public health.

Akazawa et al. (2025) studied this question.

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