Innovative approach generates oligonucleotide insecticides in 15 minutes, highlighting selectivity for non-target organisms.
The article provides basic knowledge on how to calculate selectivity of oligonucleotide pesticides when ‘genetic zipper’ (‘GZ’) technology is used to provide safety for non-target organisms. Also here we represent 100 ‘GZ’ technology-based oligonucleotide insecticides generated in 15 minutes using DNAInsector algorithm (dnainsector.com) to show that ‘GZ’ technology is amazing approach transferring us to a new oligo era of development of potent and selective oligonucleotide pesticides based on new principles prompted by nature.
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Oberemok et al. (2025) studied this question.
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