This synthesis reports multiple chemical steps including aldol addition and esterification for (±)-ganodilactone, highlighting novel vinylogous Michael addition methods.
Key Points
(±)-ganodilactone was successfully synthesized using aldol addition and Steglich esterification techniques.
The synthesis comprises five steps, showcasing an efficient pathway to ganoderma-derived meroterpenoid dimers.
Methodologies included intramolecular vinylogous Michael addition, enhancing the synthetic approach to complex molecules.
This research indicates potential new routes for synthesizing other bioactive compounds derived from Ganoderma.