This review evaluates the controversial link between MCPyV and lung cancer in smokers and non-smokers, suggesting pathways that may inform new therapies.
Key Points
The association between MCPyV infection and lung cancer remains controversial, particularly in small cell and non-small cell lung cancers.
Research shows that about 15-25% of lung cancers occur in non-smokers, indicating other factors like chronic infection are involved.
A thorough review of evidence reveals conflicting clinical findings regarding the presence of MCPyV in lung cancer cases.
Understanding the role of MCPyV in lung cancer could open avenues for new therapeutic strategies, addressing a major cancer mortality concern.