What type of study is this?

This is a Systematic Review study (also classified as: Meta-Analysis).

September 27, 2025Frontiers in ImmunologyOpen Access

Efficacy of different allergen-specific immunotherapies for the treatment of allergic rhinitis in children and adults: an umbrella review

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SLIT and SCIT showed significant efficacy for allergic rhinitis, particularly in children and adults, while ILIT had no significant effect.
Out of 16 systematic reviews and meta-analyses evaluated, only 6 demonstrated moderate quality evidence for allergen immunotherapy effectiveness.
The methodological quality assessment revealed 5 reviews rated as 'low' and 4 as 'very low', highlighting gaps in evidence strength.
The findings emphasize the need for more high-quality randomized controlled trials to better ascertain the efficacy of various allergen immunotherapies.

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Umbrella review summarizes allergen immunotherapy efficacy for allergic rhinitis, indicating mixed evidence across populations.

He et al. (2025) studied this question.

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