Case report shows improvement of facial pyoderma gangrenosum with upadacitinib and prednisone, highlighting importance of early diagnosis.
Pyoderma gangrenosum (PG) is a recurrent, painful, necrotizing ulcerative neutrophilic dermatosis. Facial PG (FPG) is a rare subtype of PG that is often misdiagnosed. A 20-year-old male with FPG showed improvement after treatment with a combination of prednisone and upadacitinib. Early diagnosis is crucial to avoid misdiagnosis.
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Ge et al. (2025) studied this question.
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