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September 27, 2025Clinical and Experimental OphthalmologyOpen Access

The Long Journey of Treatment for Wet Macular Degeneration, Is It Worth It?

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Authors

MGMark GilliesThe George Institute for Global Health

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Implication

This analysis shows declining visual acuity outcomes in patients with wet macular degeneration, suggesting the need for proactive treatment strategies.

Key Points

Outcomes suggest mean visual acuity declined by 8.1 letters after 10 years of treatment with VEGF inhibitors.
Early observational studies indicate that only 41% of eyes continued treatment, highlighting the problem of under-treatment.
Meta-analysis reveals mean visual improvement of 4.3 letters at 12 months, though treatment adherence remained inconsistent over a decade.
Proactive regimens yielded better outcomes than reactive approaches, with reasonable results observed in studies from diverse regions.

Cite This Study

Mark Gillies (2025) studied this question.

synapsesocial.com/papers/68d7be6ceebfec0fc5238051 https://doi.org/10.1111/ceo.70004

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Implication

This analysis shows declining visual acuity outcomes in patients with wet macular degeneration, suggesting the need for proactive treatment strategies.

The Long Journey of Treatment for Wet Macular Degeneration, Is It Worth It?

Discussion

Member takes

Implication

Key Points

Cite This Study

The Long Journey of Treatment for Wet Macular Degeneration, Is It Worth It?

Discussion

Member takes

Implication

Key Points

Cite This Study

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