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September 27, 2025Ukrainian journal of cardiovascular surgeryOpen Access

Lipoprotein(a) as an Independent Risk Factor and Prognostic Marker of Obstructive Coronary Artery Atherosclerosis in Young Patients: A Literature

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Authors

MHMariia B. HenehaYMYevhen Yu. MarushkoGMG. B. Mankovsky

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Overview

Literature review highlights lipoprotein(a) as a significant risk factor in young patients, suggesting new therapeutic strategies.

Key Points

  • Elevated lipoprotein(a) levels increase the risk of coronary artery disease in young patients, highlighting its prognostic value.
  • 20-30% of the general population and up to 40% of young patients have high lipoprotein(a) levels, which correlate with disease severity.
  • Current treatment options are limited, but targeted genetic therapies offer promising reductions in lipoprotein(a) levels.
  • Routine screening for lipoprotein(a) in high-risk groups could significantly improve outcomes for young patients with atherosclerosis.

Cite This Study

Heneha et al. (2025) studied this question.

synapsesocial.com/papers/68d7be70eebfec0fc52384behttps://doi.org/10.63181/ujcvs.2025.33(3).25-30
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lipoprotein(a) in clinical practice: Risk stratification and therapeutic strategies2025 · 6 citations
  2. 2Lipoprotein(a): a risk factor for atherosclerosis and an emerging therapeutic target2022 · 61 citations
  3. 3Lipoprotein(a) as a Cardiovascular Risk Factor: Clinical Significance and Therapeutic Perspectives2026
  4. 4Considerations for routinely testing for high lipoprotein(a)2022 · 8 citations
  5. 5Considerations for routinely testing for high Lp(a)2022 · 9 citations