Lupus Nephritis Developed in Patient postchemotherapy for Gestational Trophoblastic Neoplasia

The association of GTN with kidney diseases is infrequent, with scarce published case reports. This case report describes the development of lupus nephritis in a 30-year-old female following chemotherapy for high-risk gestational trophoblastic neoplasia (GTN). Despite obtaining remission from GTN, the patient presented with persistent anemia, neutropenia, and renal dysfunction, directing to additional investigation. The diagnosis of lupus nephritis was confirmed through serological tests, renal biopsy, and the identification of specific autoimmune markers. This case promotes the importance of considering autoimmune diseases, comprising lupus nephritis, in the differential diagnosis of patients with hematologic anomalies after finishing her chemotherapy for GTN.