What type of study is this?

This is a Literature Review study (also classified as: Case Report).

September 27, 2025Journal of Clinical MedicineOpen Access

Eosinophilic Myocarditis Treated with IL-5 Blockade: An Integrated Case Report and Literature Review

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Case report details eosinophilic myocarditis response to IL-5 inhibitors, indicating improved cardiac function.

IL-5 inhibitor therapy led to rapid improvement in left ventricular ejection fraction in 11 patients.
Among 21 episodes reviewed, 91% of patients had baseline ejection fraction less than 50%, highlighting severe impairment.
Therapy involving mepolizumab or benralizumab showed improvements in cardiac function and fewer steroid dependencies.
Eosinophilic infiltration was confirmed by biopsy in 87% of cases, emphasizing the inflammatory nature of this condition.

Takahashi et al. (2025) studied this question.

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