Enabling Organ- and Injury-Specific Nanocarrier Targeting via Surface-Functionalized PEG-b-PPS Micelles for Acute Kidney Injury

Q: What type of study is this?

This is a Experimental Study study.

Boaz Bishop; Swagat Sharma; Ratnakar Tiwari; Simseok A. Yuk; Sultan Almunif; Susan E. Quaggin; Evan A. Scott; Pinelopi P. Kapitsinou

doi:10.1039/d5nh00474h

January 1, 2025Nanoscale HorizonsOpen Access

Enabling Organ- and Injury-Specific Nanocarrier Targeting via Surface-Functionalized PEG-b-PPS Micelles for Acute Kidney Injury

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Key Points

Targeted delivery of nanocarriers enhanced in acute kidney injury with surface-functionalized micelles, improving treatment options.
Key evidence indicates that traditional methods limit utility in complex renal environments, requiring innovative approaches.
The approach involved developing PEG-b-PPS micelles for targeted delivery in renal settings to overcome existing challenges.
This work highlights the need for advanced nanomedicine strategies in managing kidney disease with effective targeting.

Implication

Research demonstrates improved targeted delivery of nanocarriers in acute kidney injury, suggesting new treatment avenues.

Abstract

While nanomedicine holds great promise for kidney disease, targeted delivery remains a major challenge. Most nanocarriers rely on passive accumulation or epithelial-specific ligands, limiting their utility in complex, inflamed renal...

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Cite This Study

Bishop et al. (2025) studied this question.

synapsesocial.com/papers/68d9051441e1c178a14f4b2b https://doi.org/10.1039/d5nh00474h

View Full Paper

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Enabling Organ- and Injury-Specific Nanocarrier Targeting via Surface-Functionalized PEG-b-PPS Micelles for Acute Kidney Injury

Key Points

Implication

Abstract

Discussion

Cite This Study

Enabling Organ- and Injury-Specific Nanocarrier Targeting via Surface-Functionalized PEG-b-PPS Micelles for Acute Kidney Injury

Key Points

Implication

Abstract

Discussion

Cite This Study

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