Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 28, 2025AddictionOpen Access

Nicotine pouches and clinical outcomes related to smoking cessation: A systematic review of randomized trials

View Full Paper
Ask AI
Bookmark
Share

Authors

JHJavad HeshmatiUniversity of OttawaSSSpencer ShahenAction on Smoking and HealthEric BatesEric BatesInterventional / Structural Cardiology

Discussion

Loading...

Member takes

Implication

Systematic review evaluates nicotine pouches for smoking cessation in adults, highlighting user satisfaction and urges to smoke.

Key Points

  • Nicotine pouches showed improved user satisfaction over gum but were less satisfying than cigarettes, indicating potential limitations in acceptability.
  • In a pilot trial, daily cigarette consumption decreased from 15.0 to 8.3 with 4 mg nicotine pouches, suggesting a possible benefit in smoking reduction.
  • Systematic review of randomized trials encompassing 269 adult smokers aimed to assess the clinical impact of nicotine pouches on cessation outcomes.
  • Findings indicate generally mild adverse events with no serious incidents, but no significant evidence supports increased smoking cessation rates compared to controls.

Cite This Study

Heshmati et al. (2025) studied this question.

synapsesocial.com/papers/68d9052141e1c178a14f5103https://doi.org/10.1111/add.70193
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Small pouches, but high nicotine doses—nicotine delivery and acute effects after use of tobacco-free nicotine pouches2024 · 62 citations
  2. 2Beyond smoking: Risk assessment of nicotine in pouches2024 · 15 citations
  3. 3Heated Tobacco Products: Insights into Composition and Toxicity2023 · 109 citations
  4. 4Health Effects of Tobacco at the Global, Regional, and National Levels: Results From the 2019 Global Burden of Disease Study2021 · 155 citations
  5. 5Electronic cigarette use and smoking initiation among youth: a longitudinal cohort study2017 · 184 citations