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September 28, 2025Open Access

Multivariate Regression Analysis of Risk Factors for Lower Extremity Varicose Veins Based on VCSS Scores

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Authors

YZYi ZhangDLDaozheng LvQLQiang Li

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Overview

Cross-sectional analysis identifies key risk factors associated with varicose veins severity, suggesting interventions. Key findings highlight the impact of behavioral factors and family history.

Key Points

  • Patients with a family history showed the strongest link to increased VCSS scores, indicating genetic risk factors are crucial.
  • Significant associations between high VCSS scores and obesity, smoking, and diabetes underscore the need for lifestyle interventions.
  • The use of a Generalized Additive Model allowed for a nuanced understanding of the relationships between risk factors and disease severity.
  • Targeted management strategies can help patients mitigate risks, including compression stockings for those with behavioral problems and smoking cessation.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68d9052941e1c178a14f57bdhttps://doi.org/10.21203/rs.3.rs-7318976/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Varicose veins of lower extremities: Insights from the first large-scale genetic study2019 · 81 citations
  2. 2Varicose veins of lower extremities: insights from the first large-scale genetic study2018 · 10 citations
  3. 3Predictive factors for iliac vein compression syndrome in patients with varicose veins2024 · 1 citations
  4. 4Factors affecting adherence to compression therapy in postoperative patients with lower limb varicose veins2025 · 2 citations
  5. 5Factors Associated With Quality of Life in Patients With Venous Leg Ulcers in a Community Setting: A Cross‐Sectional Study2025