September 28, 2025Asian Journal of Pediatric ResearchOpen Access

Effect of Levetiracetam Monotherapy on Serum Calcium, Vitamin D and Seizure Control in Children with Epilepsy: A Longitudinal Observational Study

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Levetiracetam monotherapy led to 64.5% of children becoming seizure-free after 6 months, showing its efficacy.
Significant declines in serum calcium and vitamin D were recorded, with calcium dropping from 9.18 to 9.01 mg/dl and vitamin D from 26.04 to 25.09 ng/ml.
Neuropsychiatric side effects were noted in 44.3% of children, highlighting the importance of monitoring these effects in treatment.
The study emphasizes the need for clinicians to address the decline in bone health markers associated with levetiracetam.

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Implication

Longitudinal observational study shows levetiracetam improves seizure control in children with epilepsy, suggesting attention to calcium and vitamin D levels.

Cite This Study

Halder et al. (2025) studied this question.

synapsesocial.com/papers/68d90a0141e1c178a14f5f97 https://doi.org/10.9734/ajpr/2025/v15i9478

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Implication

Longitudinal observational study shows levetiracetam improves seizure control in children with epilepsy, suggesting attention to calcium and vitamin D levels.

Effect of Levetiracetam Monotherapy on Serum Calcium, Vitamin D and Seizure Control in Children with Epilepsy: A Longitudinal Observational Study

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Implication

Cite This Study

Effect of Levetiracetam Monotherapy on Serum Calcium, Vitamin D and Seizure Control in Children with Epilepsy: A Longitudinal Observational Study

Key Points

Discussion

Implication

Cite This Study

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