The role of rehabilitation in Post-COVID-19 syndrome (PCS) recovery: An effectiveness study

Introduction: This study aimed to measure the effectiveness of our rehabilitation program for patients with Post-COVID-19 syndrome (PCS) by comparing their symptoms before and after intervention. Method: A prospective cohort study was conducted with adults referred to a COVID clinic over 6 months. Participants ( n = 48) were assessed at three timepoints and served as their own control, allowing comparison of symptom changes during a 6-week waiting period versus a 6-week rehabilitation period. The virtual group rehabilitation program, led by occupational therapy and physiotherapy, offered practical strategies, peer support and guidance to enhance daily function and quality of life. Results: Of 117 invited, 48 (41%) consented and completed baseline measures. After excluding incomplete data, 36 participants were included in the analysis. Unlike many PCS studies lacking comparators, this within-subject design strengthened the findings. No significant changes occurred during the waiting period, but significant improvements were seen post-intervention: C19-YRSm: 29 ± 1.7 (baseline), 28.3 ± 1.7 (week 6, p = 0.34), improving to 18.3 ± 1.9 (week 12, p < 0.001). MFIS: 54.1 ± 2.8 (baseline), 54.2 ± 2.6 (week 6, p = 0.18), improving to 36.8 ± 3.2 (week 12, p < 0.001). Conclusion: A virtual MDT-led rehabilitation program significantly reduced PCS symptoms, supporting the value of structured rehabilitation in PCS recovery.