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September 28, 2025International Journal of Pharmaceutical Quality Assurance

Antimicrobial Resistance Profiles of Bacterial Isolates from Bloodstream Infections in a Tertiary Care Hospital in Western India

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Authors

MBManjula J BabariyaMVManik VohraJSJitender Solanki

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Overview

Observational study evaluated bacterial pathogens and their resistance patterns in bloodstream infections, highlighting antimicrobial stewardship.

Key Points

  • Of the 2,290 blood samples, only 199 (8.7%) were culture-positive for pathogens, revealing a concerning prevalence of bacterial infections.
  • Escherichia coli and Klebsiella pneumoniae made up a significant portion of infections, with resistance observed against third-generation cephalosporins and fluoroquinolones.
  • Susceptibility testing employed disk diffusion and automated methods, following CLSI 2023 guidelines, ensuring reliable identification of resistance patterns.
  • The findings emphasize the urgent need for routine susceptibility testing and local antibiogram-guided therapy to combat multidrug-resistant bacteria.

Cite This Study

Babariya et al. (2025) studied this question.

synapsesocial.com/papers/68d90bc641e1c178a14f6dcdhttps://doi.org/10.25258/ijpqa.16.5.22
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antimicrobial sensitivity trends and bacterial profile of bloodstream infections: A retrospective study2026
  2. 2Microbiological profile and antimicrobial resistance patterns of bloodstream infections in a tertiary care hospital in eastern India2025
  3. 3ANTIBIOGRAM ANALYSIS OF BLOODSTREAM BACTERIAL ISOLATES FROM INTENSIVE CARE UNITS2025
  4. 4A Retrospective Observational Study of the Microbial Etiology and Antimicrobial Susceptibility Patterns of Blood Cultures From ICU Patients at a Healthcare Facility in North India2024 · 2 citations
  5. 5Bloodstream infections: trends in etiology and antimicrobial resistance in 10 years in Eastern Nepal2025 · 7 citations