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September 28, 2025Advanced Healthcare Materials

Hybrid Ultrasound‐Enhanced and Self‐Cascade‐Catalysis‐Mediated System with Lewis Acid Active Centers for Treating MRSA‐Infected Osteomyelitis

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Authors

PLPanyue LiuSLShuxin LuHCHao Cheng

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Overview

This system reduces MRSA by 5 logs in 15 minutes, suggesting enhanced treatment for osteomyelitis.

Key Points

  • The hybrid system reduced MRSA survival by 5 logs in 15 minutes, indicating its effectiveness in treatment.
  • In vivo results showed ultrasound-activated Cu/ZM-Ca cleared 99.5% of bacteria, significantly improving healing.
  • The electron-pair catalytic mechanism allows for effective H2O2 cleavage, enhancing reactive oxygen species generation.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68d90bc641e1c178a14f7035https://doi.org/10.1002/adhm.202502586
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