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September 28, 2025

Aging, Alzheimer's disease, and stroke: A 25-year longitudinal analysis of U.S. mortality trends.

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Authors

MAMuhammad Faizan AliJinnah Postgraduate Medical CenterHAHusnain AhmadSewanee: The University of the SouthMHMohamed Fawzi HemidaCairo University

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Implication

Longitudinal analysis reveals disparities in stroke-related mortality among Alzheimer's patients by sex and race, indicating a need for targeted interventions.

Key Points

  • Stroke-related mortality among Alzheimer's patients decreased, yet disparities persist across demographics and regions.
  • From 1999 to 2023, 154,323 deaths related to strokes in Alzheimer's patients were recorded, with AAMRs declining significantly during this period.
  • Data sourced from CDC WONDER showed the age-adjusted mortality rates for stroke decreased from 19.4 to 10.5, with the Northeast region showing the most significant decline.
  • Significant racial and geographic disparities exist, highlighting the need for targeted health interventions in underrepresented communities.

Cite This Study

Ali et al. (2025) studied this question.

synapsesocial.com/papers/68d913ab4ddcf71ba560bd00https://doi.org/10.1177/13872877251380689
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sex Differences in the Clinical Presentation, Resource Use, and 3-Month Outcome of Acute Stroke in Europe2003 · 659 citations
  2. 2Prevalence of stroke and associated risk factors among elderly patients in a primary care setting: A retrospective cohort study2025 · 5 citations
  3. 3Rural-Urban Disparities2021 · 218 citations
  4. 4Racial and ethnic differences in cognitive function among older adults in the USA2016 · 151 citations