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September 28, 2025

Synergistic effect of exposure to ambient ozone and fine particulate matter on embryonic developmental outcomes among an assisted reproductive population.

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Authors

HSHao ShiCHChenxiao HanJHJian Hou

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Overview

Analysis reveals that ozone and PM2.5 exposure reduces fertilization and embryo rates in assisted reproductive populations, suggesting targeted air quality improvements.

Key Points

  • Exposure to PM2.5 and ozone negatively impacts normal fertilization rates, high-quality embryo rates, and blastocyst formation.
  • Significant associations were found in a population of 17,941 couples undergoing IVF, highlighting environmental concerns.
  • Generalized additive models were used to assess the synergistic effects of air pollution on embryological outcomes.
  • Findings indicate a need for coordinated control of ozone and PM2.5 levels to protect embryonic development.

Cite This Study

Shi et al. (2025) studied this question.

synapsesocial.com/papers/68d913ab4ddcf71ba560bd41https://doi.org/10.1039/d5em00316d
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Also Consider

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  1. 1Mixed effects of ambient air pollutants on oocyte-related outcomes: A novel insight from women undergoing assisted reproductive technology2024 · 13 citations
  2. 2Maternal Exposure to Surface Ozone and Reduced Fecundity in China: Evidence from a Nationwide Survey2025 · 4 citations
  3. 3Generalized additive models: Building evidence of air pollution, climate change and human health2019 · 475 citations
  4. 4Association between ambient air pollution and pregnancy outcomes in patients undergoing in vitro fertilization in Shanghai, China: A retrospective cohort study2021 · 68 citations
  5. 5Association between exposure to ambient air pollutants and the outcomes of in vitro fertilization treatment: A multicenter retrospective study2021 · 69 citations