Factors related to Recurrence Rates of Extramammary Paget Disease: Case Series and Literature Review

Extramammary Paget Disease (EMPD) is a rare cutaneous malignant lesion. Surgical resection is the primary treatment. However, the ideal surgical margin remains uncertain. This study aimed to investigate the correlation between different margins and EMPD recurrence rates. A total of 35 EMPD patient who underwent surgical resection between 2008-2018. The study demonstrated that surgical margin of 2 cm signified the outcome of local recurrence with 20.8% in the <2 cm group and no local recurrence (0.0%) in the ≥2 cm group (p=0.157). The tumor size statistical significantly affected the local recurrence at 9 cm (p<0.05). Other managements had no statistical significance to local recurrent rate. Surgical margin size more than 2 cm is suggested for wide excision of EMPD patients, considered the recurrent percentage and outcome in this study.