September 28, 2025ScienceOpen Access

What if NIH had been 40% smaller?

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A 40% reduction in NIH funding impacts drug-linked research widely, leading to fewer discoveries and innovations.
Key evidence shows that decreased funding correlates with a decline in research outputs and drug development.
This analysis uses a historical simulation to explore the implications of reduced NIH funding on drug research.
The findings highlight the critical role of NIH funding in fostering drug innovation and public health advancement.

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Simulated reductions in NIH funding reveal significant impacts on drug research, suggesting policy implications.

Replaying history with less NIH funding shows widespread impacts on drug-linked research

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Azoulay et al. (2025) studied this question.

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Simulated reductions in NIH funding reveal significant impacts on drug research, suggesting policy implications.

Replaying history with less NIH funding shows widespread impacts on drug-linked research