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September 29, 2025Rheumatology (Bulgaria)Open Access

Malt–lymphomas in Primary Sjögren's Syndrome

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Authors

MMMaria Panchovska - Mocheva

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Overview

Observational analysis finds a 44-fold increased lymphoma risk in Sjögren's syndrome patients, highlighting chronic inflammation's role.

Key Points

  • The study shows that patients with Sjögren's syndrome have a significantly higher risk of developing lymphomas, reaching up to 44 times compared to the general population.
  • MALT-lymphomas are a notable type of lymphoma occurring in these patients, characterized by an indolent course and linked to chronic inflammation.
  • Immune processes and genetic factors are crucial in the malignant transformation associated with Sjögren's syndrome, particularly influenced by Helicobacter pylori.
  • This research emphasizes the need for monitoring lymphoma development in Sjögren's syndrome patients, considering their increased risk.

Cite This Study

Maria Panchovska - Mocheva (2025) studied this question.

synapsesocial.com/papers/68da58dcc1728099cfd1146dhttps://doi.org/10.35465/33.1.2025.pp57-69
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