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September 30, 2025Annals of HematologyOpen Access

Genetic insights into myeloproliferative neoplasms and unusual sites thrombosis

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A high prevalence of unclassifiable myeloproliferative neoplasms was found among patients with unusual site thrombosis.
JAK2 p.V617F mutation was identified in 86.4% of cases, linking it to increased risk of thrombotic events.
The analysis included 44 patients with myeloproliferative neoplasms using next-generation sequencing to identify mutations.
Absence of KIT mutations indicated poorer thrombotic recurrence-free survival, emphasizing its negative prognostic role.

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Retrospective analysis explores genetic factors in thrombosis linked to myeloproliferative neoplasms, highlighting diagnostic challenges.

Morsia et al. (2025) studied this question.

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