Synthesis of (Camphor-3-yl)acetic Acid-Derived Pyrazoles

Q: What type of study is this?

This is a Experimental Study study.

Luka Ciber; Helena Brodnik; Nejc Petek; Franc Požgan; Jurij Svete; Bogdan Štefane; Uroš Grošelj

doi:10.3390/m2058

September 12, 2025MolbankOpen Access

Synthesis of (Camphor-3-yl)acetic Acid-Derived Pyrazoles

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Key Points

Two pyrazole derivatives were successfully synthesized from camphor-3-yl acetic acid using a three-step process.
The stereochemistry of the new stereogenic center was confirmed with both NOESY measurements and single crystal X-ray analysis.
Each pyrazole derivative was thoroughly characterized, validating the synthetic method employed.
The approach demonstrates the effectiveness of using camphor-3-yl acetic acid as a precursor for creating complex pyrazole compounds.

Implication

Two pyrazole derivatives were synthesized from camphor-3-yl acetic acid, confirming stereochemistry through NOESY and X-ray analysis.

Abstract

Two pyrazole derivatives were prepared in three steps from (camphor-3-yl)acetic acid. The pyrazole derivatives were fully characterized. The stereochemistry at the newly formed stereogenic center was confirmed by NOESY measurements and single crystal X-ray analysis.

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Cite This Study

Ciber et al. (2025) studied this question.

synapsesocial.com/papers/68dc1e308a7d58c25ebb127f https://doi.org/10.3390/m2058

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Synthesis of (Camphor-3-yl)acetic Acid-Derived Pyrazoles

Key Points

Implication

Abstract

Discussion

Cite This Study

Synthesis of (Camphor-3-yl)acetic Acid-Derived Pyrazoles

Key Points

Implication

Abstract

Discussion

Cite This Study

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