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September 30, 2025Journal of Clinical MedicineOpen Access

Mucosal Melanoma of the Oral Cavity: Prognostic Factors Influencing Patient Survival Outcomes

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Authors

JTJakub TarnawskiBWB. WojciechowskaAPAdam Polcyn

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Overview

Systematic review identifies clinical and molecular factors impacting survival outcomes in mucosal melanoma, suggesting critical insights for prognosis.

Key Points

  • Favorable prognostic indicators included preserved expression of BAP1 and tumor-infiltrating lymphocytes, contributing to better outcomes.
  • Analysis of 43 patients revealed a potential for long-term survival despite the generally poor prognosis associated with the condition.
  • Younger patients without lymphadenopathy or distant metastasis showed longer survival periods, indicating the importance of these factors.
  • Exceptions in survival underscore that not all cases conform to existing clinical and molecular prognostic criteria, highlighting complexity.

Cite This Study

Tarnawski et al. (2025) studied this question.

synapsesocial.com/papers/68dc1e438a7d58c25ebb231fhttps://doi.org/10.3390/jcm14196863
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Survival and prognostic factors in mucosal melanomas of the oral cavity: A meta-analysis2025
  2. 2Mucosal melanoma: clinicopathological, molecular and prognostic features in a retrospective cohort2026
  3. 3Prognostic Predictors of Oral Mucosal Melanoma—A Systematic Review and Meta‐Analysis2025
  4. 4A Retrospective Analysis of the Prognostic Factors and Adverse Events in the Treatment of Mucosal Melanoma in a Single Centre2024 · 2 citations
  5. 5A case series on oral mucosal melanoma: Presenting beyond the typical2026