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September 30, 2025Organic Chemistry Frontiers

Facile Access to Indolo[2,3-b]quinoline Alkaloids via DMSO-Mediated Cascade Cyclization: Unveiling Their Photophysical Potential

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The effective synthesis method yields indolo[2,3-b]quinoline alkaloids using C3-alkylated indole.
This DMSO-mediated approach provides a significant advancement in producing these compounds efficiently.
The synthetic strategy showcases potential applications in exploring the photophysical properties of the alkaloids.
The use of HCl in the methodology suggests further optimization possibilities for enhancing yields and reaction conditions.

Implication

This methodology demonstrates a streamlined synthesis of indolo[2,3-b]quinoline alkaloids mediated by DMSO, highlighting their photophysical potential.

Abstract

A streamlined and efficient synthetic strategy has been established for the construction of Indolo[2,3-b]quinolines, utilizing C3-alkylated indole as the starting material and mediated by DMSO and HCl. This methodology enables...

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Cite This Study

Nataraj et al. (2025) studied this question.

synapsesocial.com/papers/68dc1e438a7d58c25ebb2513 https://doi.org/10.1039/d5qo01193k

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Implication

This methodology demonstrates a streamlined synthesis of indolo[2,3-b]quinoline alkaloids mediated by DMSO, highlighting their photophysical potential.

Facile Access to Indolo[2,3-b]quinoline Alkaloids via DMSO-Mediated Cascade Cyclization: Unveiling Their Photophysical Potential

Key Points

Implication

Abstract

Discussion

Cite This Study

Facile Access to Indolo[2,3-b]quinoline Alkaloids via DMSO-Mediated Cascade Cyclization: Unveiling Their Photophysical Potential

Key Points

Implication

Abstract

Discussion

Cite This Study

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