September 30, 2025BiomedicinesOpen Access

Immune Dysregulation in Sepsis. A Narrative Review for the Clinicians

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Discussion

Narrative review highlights immune dysregulation and emerging diagnostic strategies for sepsis, suggesting potential therapeutic approaches.

Immune dysregulation leads to significant clinical challenges with rapid progression in sepsis, complicating patient outcomes.
Novel biomarkers, including cytokines and microRNA levels, play crucial roles in guiding personalized treatment strategies for sepsis.
Understanding immune imbalance in sepsis is pivotal for optimizing treatment approaches and reducing mortality rates.
The review emphasizes the need for clinical validation of emerging therapeutic methods like immunomodulators to enhance patient outcomes.

Valsamaki et al. (2025) studied this question.

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Narrative review highlights immune dysregulation and emerging diagnostic strategies for sepsis, suggesting potential therapeutic approaches.