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This clinical trial evaluates oral and topical vitamin D's impact on localized psoriasis, suggesting improved outcomes compared to steroids.
Background: Aim: Topical steroid use in Psoriasis is rampant inducing skin atrophy, telangectasia, striae & superficial dermatophytosis We are conducting a study for knowing the efficacy of oral Vitamin D supplementation and topical application of Vitamin D in the management of localised chronic plaque Psoriasis Vulgaris so as to reduce the long term use of topical steroids and replacing it with topical Vitamin D supplements (Calcipotriol) & Oral Vitamin D supplementation (60000 IU/ once a week for four weeks). This study Results: shows sharp correlation of Vitamin-D supplementation with Psoriasis immunopathology and in improving the treatment response. The patients were commonly observed between 11-20years of age and female predilection was mostly observed. Topical application of vitamin D is more efficient than only oral vitamin D supplement in the management of localised chronic plaque psoriasis.
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Nikhat et al. (2025) studied this question.
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