Synthesis of sulfilimines via electron donor−acceptor complexes

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This is a Experimental Study study.

Ke Wu; Junliang Zhang; Junfeng Yang

doi:10.1039/d5qo01017a

January 1, 2025Organic Chemistry Frontiers

Synthesis of sulfilimines via electron donor−acceptor complexes

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Key Points

This synthesis efficiently produces sulfilimines, showcasing a novel method in chemical biology and medicinal chemistry.
Key steps involve arylation, alkylation, and alkenylation of sulfenamides using copper catalysis.
The method utilizes readily available thianthrenium as an essential reagent for the reaction.
The findings may enable further exploration of sulfur-containing compounds in various applications.

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Implication

Research demonstrates efficient synthesis of sulfilimines from sulfenamides via alkylation and arylation, highlighting new pathways in medicinal chemistry.

Abstract

Sulfur-containing compounds have broad application prospects in chemical biology and medicinal chemistry. Herein we reported a Cu-catalyzed sulfilimine synthesis via arylation, alkylation and alkenylation of sulfenamides using readily accessible thianthrenium...

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Wu et al. (2025) studied this question.

synapsesocial.com/papers/68dc262a8a7d58c25ebb3641 https://doi.org/10.1039/d5qo01017a

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Synthesis of sulfilimines via electron donor−acceptor complexes

Key Points

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Implication

Abstract

Discussion

Cite This Study

Synthesis of sulfilimines via electron donor−acceptor complexes

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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