Evaluation of Antioxidant and Anti-psoriatic Activities of Purple Sweet Potato (Ipomoea batatas L.) Leaves Aqueous Extract on Imiquimod-induced Psoriasis-like Dermatitis
Experimental analysis reveals antioxidant and anti-psoriatic effects in imiquimod-induced psoriasis model in BALB/c mice, suggesting natural therapeutic potential.
Key Points
The aqueous extract of purple sweet potato leaves demonstrated significant anti-psoriatic effects in mice treated with imiquimod.
In vivo studies showed a dose-dependent improvement in psoriasis severity index scores with topical application of PSPLAE.
Phytochemical analysis indicated noteworthy levels of total phenolic and flavonoid content in the purple sweet potato leaves extract.
The antioxidant capacity measured via DPPH assay displayed a moderate correlation with total phenolic content, implying potential therapeutic benefits.