Gold‐Catalyzed Enantioselective Synthesis of Axially Chiral Compounds

Q: What type of study is this?

This is a Literature Review study.

Yirong Dong; Tao Wang

doi:10.1002/adsc.70139

September 28, 2025Advanced Synthesis & Catalysis

Gold‐Catalyzed Enantioselective Synthesis of Axially Chiral Compounds

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Key Points

Gold-catalyzed methods enable efficient synthesis of axially chiral compounds, which are important for pharmaceuticals and materials.
The review categorizes published results by chiral axis type, addressing challenges in ligand design and reaction scope.
Mechanistic insights into these reactions are detailed, which may assist in overcoming existing synthetic challenges.
Future directions in gold-catalyzed synthesis indicate potential for developing new ligands and expanding the scope of reactions.

Implication

This review highlights gold-catalyzed enantioselective synthesis of axially chiral compounds, emphasizing structural insights and future challenges.

Abstract

This review provides an overview of the advances in gold‐catalyzed synthesis of axially chiral compounds. The published results to date on this topic are categorized by the type of chiral axis, highlighting the structure of ligands, the reaction scope, and mechanistic insights. The challenges and the future directions of this field are also discussed.

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Cite This Study

Dong et al. (2025) studied this question.

synapsesocial.com/papers/68dd89defe798ba2fc497d41 https://doi.org/10.1002/adsc.70139

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Gold‐Catalyzed Enantioselective Synthesis of Axially Chiral Compounds

Key Points

Implication

Abstract

Discussion

Cite This Study

Gold‐Catalyzed Enantioselective Synthesis of Axially Chiral Compounds

Key Points

Implication

Abstract

Discussion

Cite This Study

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