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October 1, 2025Journal of Health Population and NutritionOpen Access

The association between Helicobacter pylori infection and diabetes mellitus: an updated meta-analysis of 45 case-control studies

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Authors

HHHabib HadianfardRDRamyar Rahimi DarehbaghKAKimya Ahmadpooryan

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Overview

Meta-analysis of 45 case-control studies shows H. pylori increases diabetes risk, suggesting testing benefits.

Key Points

  • H. pylori infection significantly increases the risk of diabetes mellitus, particularly type 2 diabetes.
  • The pooled odds ratio indicates a 1.547 times higher risk of developing diabetes in individuals with H. pylori.
  • Systematic review and meta-analysis following PRISMA guidelines included 45 case-control studies from various sources.
  • Considering H. pylori testing in diabetes management may benefit high-risk populations across geographic regions.

Cite This Study

Hadianfard et al. (2025) studied this question.

synapsesocial.com/papers/68dd89e6fe798ba2fc49824ehttps://doi.org/10.1186/s41043-025-01088-7
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of Helicobacter pylori infection with complications of diabetes: a single-center retrospective study2024
  2. 2Causal relationships of Helicobacter pylori and related gastrointestinal diseases on Type 2 diabetes: Univariable and Multivariable Mendelian randomization2024 · 2 citations
  3. 3Evaluation of Some Immunological Parameters in Type II Diabetic Patients Infected With Helicobacter pylori2025
  4. 4Association of H. pylori IgG and CagA-IgG with some immunological and biochemical parameters in diabetic patients.2024
  5. 5Association between Helicobacter pylori infection and type 2 diabetes mellitus: a retrospective cohort study and bioinformatics analysis2024 · 2 citations