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October 1, 2025Bitlis Eren Üniversitesi Fen Bilimleri DergisiOpen Access

Design, Synthesis and In Vitro Biological Assessment Of Novel 2-(3-Alkyl/Aryl-4,5-Dihydro-1h-1,2,4-Triazol-5-One-4-Yl)AzomethinePhenyl 2,5-Dichlorobenzenesulfonates Molecules as Antioxidant and Antibacterial Agents

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Authors

FAFevzi AytemizHYHaydar Yüksek

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Overview

Synthesis of new triazole compounds with antioxidant and antimicrobial properties, suggesting enhanced therapeutic potential.

Key Points

  • Compounds 4a-i exhibited significant antioxidant properties, showing metal chelation activity comparable to α-tocopherol.
  • Among the tested compounds, 4a demonstrated superior antimicrobial activity compared to some standard antibiotics.
  • The synthesis of these new triazole derivatives achieved yields exceeding 90%, ensuring effective production of targeted compounds.
  • The study utilized NMR and IR spectroscopy for the structural elucidation of the synthesized compounds, confirming their identities.

Cite This Study

Aytemiz et al. (2025) studied this question.

synapsesocial.com/papers/68dd91c7fe798ba2fc4984e1https://doi.org/10.17798/bitlisfen.1655093
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