What type of study is this?

This is a Cohort Study study (also classified as: Quantitative Study).

October 1, 2025Open Access

Benchmarking the Reproducibility of Brain MRI Segmentation Across Scanners and Time

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Study benchmarks segmentation methods FastSurfer and SynthSeg in MRI, highlighting reproducibility challenges across scans.

Substantial volume variation of 7-8% in the amygdala and ventral diencephalon complicates tracking small changes.
Segmentation pipelines were assessed using metrics like Dice coefficient and Mean Absolute Percentage Error.
Two datasets, a 17-year longitudinal cohort and a 9-site test-retest cohort, were utilized for evaluation.
Proposed strategies to enhance reliability emphasize the necessity for harmonization in neuroimaging practices.

Kondrateva et al. (2025) studied this question.

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