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October 1, 2025Journal of Intensive Care MedicineOpen Access

Is Clinical Outcome Pathogen Related? Characteristics and Outcomes of ICU Patients with Severe Acute Respiratory Infections: Focusing on Respiratory Syncytial Virus, Human Metapneumovirus, Influenza Virus, and Parainfluenza Virus

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Authors

SBSjoerd van der BieErasmus MC RFRamon C. FluitErasmus MC TNTobias R. NeijzenSpaarne Ziekenhuis

Discussion

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Implication

Retrospective cohort analysis shows mortality rates similar among ICU patients with SARI from RSV, HMPV, IV, and PIV, indicating no virus-related outcome disparities.

Key Points

Patients with RSV showed a higher prevalence of hematological malignancies compared to other virus groups.
Median ICU stay for patients was four days, with no significant length of hospital stay differences across viral infections.
Mortality rates were not significantly different between virus groups: RSV 25.5%, HMPV 15%, IV 24.6%, and PIV 20.5%.
Higher ROX-index and co-infections were noted in patients experiencing failure of noninvasive ventilation.

Cite This Study

Bie et al. (2025) studied this question.

synapsesocial.com/papers/68dd91cbfe798ba2fc498a55 https://doi.org/10.1177/08850666251375938

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Implication

Retrospective cohort analysis shows mortality rates similar among ICU patients with SARI from RSV, HMPV, IV, and PIV, indicating no virus-related outcome disparities.

Is Clinical Outcome Pathogen Related? Characteristics and Outcomes of ICU Patients with Severe Acute Respiratory Infections: Focusing on Respiratory Syncytial Virus, Human Metapneumovirus, Influenza Virus, and Parainfluenza Virus

Discussion

Member takes

Implication

Key Points

Cite This Study

Is Clinical Outcome Pathogen Related? Characteristics and Outcomes of ICU Patients with Severe Acute Respiratory Infections: Focusing on Respiratory Syncytial Virus, Human Metapneumovirus, Influenza Virus, and Parainfluenza Virus

Discussion

Member takes

Implication

Key Points

Cite This Study

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