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October 1, 2025Frontiers in NutritionOpen Access

Gut microbiota and targeted metabolomics of short-chain fatty acid reveals Qing-Re-Zao-Shi-Jian-Pi prescription on glucose and lipid metabolism in type 2 diabetic mice

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Authors

JLJing LiuMQMeng QinHWHaidan Wang

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Overview

Observational study reveals that Qing-Re-Zao-Shi-Jian-Pi improves glucose metabolism in mice, suggesting alterations in gut microbiota.

Key Points

  • Qing-Re-Zao-Shi-Jian-Pi significantly reduces fasting blood glucose and triglyceride levels in type 2 diabetic mice.
  • A notable increase in butyrate levels and a shift in gut microbiota composition were observed after treatment.
  • Utilizing high-fat diets and streptozocin injections, a T2D mouse model was established to evaluate effects of the prescription.
  • The study suggests this traditional Chinese medicine could provide new preventive strategies against type 2 diabetes.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68dd91dafe798ba2fc49952fhttps://doi.org/10.3389/fnut.2025.1626778
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