Abstract Background: In the genus Candida , there are more than 200 yeast species, although only around 10% of them have been found to be dangerous to people and some other animals. Invasive candidiasis is the most prevalent invasive fungal infection examined, and Candida albicans ( C. albicans ) is the most common causal pathogen. Objectives: The current investigation is to isolate and identify Candida spp. from various clinical specimens and to calculate multiple drug resistance (MDR) index and the ability of biofilm formation. Materials and Methods: One hundred (100) different clinical samples (ear, mouth, vagina, skin, blood, and urine) were collected from patients who attended Gazi Al Hariri Hospital, Baghdad Teaching Hospital in Medical City and Al-Yarmouk Teaching Hospital. Candida spp. were identified using selective medium. Furthermore, antifungal susceptibility and MDR index were evaluated. Results: The results of isolation and identification for Candida species were revealed that Candida parapsilosis isolated in a high percentage (27.7%) followed by Candida glabrata (22.2%), the lowest percentage was recorded in Candida tropicalis , Candida krusei (5.50%), while the MDR index of isolated Candida spp. toward the antifungal in the current study showed that Candida lusitaniae and Candida krusei and Candida parapsilosis were (100%), the biofilm formation strength was different between the isolates Candida tropicalis and Candida rugosa showed strong biofilm formation strength. Conclusion: Candida parapsilosis was isolated in high percentage. Candida lusitaniae , Candida krusei , and Candida parapsilosis were the most resistant to the antifungal agents. Candida lusitaniae , Candida glabrata , Candida tropicalis , and Candida rugosa revealed strong biofilm formation.
Al-Ameri et al. (Tue,) studied this question.