Analysis and evaluation of the clinical efficacy of treatment of chronic periodontitis using stromal vascular fraction and native platelet autoplasm: A controlled randomized clinical study

Periodontitis is one of the most common dental diseases, polyetiology, is the cause of constant discomfort in the oral cavity, in the form of inflammation and sensitivity of the gums, limiting physiological needs, such as eating and communication. Despite the availability of various treatment methods (conservative, surgical, physiotherapeutic), the need for new, effective methods remains relevant. Autoplasma-gum plasmolifting has been widely used in dentistry for more than 20 years, but the stromal-vascular fraction is just beginning its journey. Why not combine two safe regenerative masses into one, achieving a quick effect with long-lasting remission? We treated 85 patients aged 36 to 65 with chronic periodontitis (CP). The patients were divided into 2 groups depending on the type of treatment: in the I-main group (OG), 43 patients with CH were injected in addition to standard treatment a mixture of stromal-vascular fraction (SVF) and native platelet autoplasm (TAP) was injected into the inflamed interdental papillae in the II control group (CG) of 42 patients with CP who received basic treatment. All patients underwent a dental examination, and a periodontal chart was compiled, which included the following indicators: the depth of periodontal pockets, pathological tooth mobility, bone tissue resorption, a computed tomography scan, the Muller bleeding index and hygiene index, and the condition of periodontal tissue microcirculation. Results. After performing SRF and TAP in the main group, all indicators improved, namely, the depth of periodontal pockets decreased by 1.4 mm, bone tissue resorption by 25.5%, tooth mobility decreased by degree, increased the volume of blood flow perfusion, reaching the norm of 30.02±4.36 perf. units, the values of the indices also showed themselves in a better way. Conclusion. When treating the method of SRF and TAP, we achieved a stable remission, restoration of the periodontal attachment and the level of bone tissue mineralization in the interdental septa of the alveolar bones.