Lecture highlights the challenges in diagnosing amyotrophic lateral sclerosis due to diverse factors, suggesting a need for further investigation.
Amyotrophic lateral sclerosis is one of the most prevalent lethal neurodegenerative multifactorial diseases with selective lesion of the central and peripheral motor neurons and often with genetic predisposition and participation of the environmental factors (sex, age, exogenuos toxins, traumas, etc.). Clinical data and electroneuromyography (ENMG) changes are the main diagnostic markers of the illness. However, the prevalent symptomatic syndrome of the motor neuron involvement makes it difficult to diagnose the true illness, and the absence of pathogenetic therapy demands further scientific study
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Latysheva et al. (2014) studied this question.
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