[Mpox Virus: From Virology to Clinical Aspects. An Update].

Mpox (formerly known as monkeypox) is an emerging zoonosis caused by the Mpox virus (MPXV), which has raised global concern. To explore and integrate the advances in the knowledge of the pathogenesis, clinical features, and therapeutic approaches to the Mpox virus in the context of our country. A qualitative study through a narrative review of documents related to the international mpox epidemic. According to the search criteria and relevance, 10 articles were included. A general overview of the scientific evidence in microbiological and clinical aspects is presented, considering Chilean public health policies. Clinicians should understand the pathogenesis, replication cycle, and clinical manifestations of MPXV to make an early diagnosis, develop therapeutic alternatives, and prevent its transmission within the community.